| | | | | | | | | | |  | Major Transactions |
| | | | Thursday, October 13th, 1966 | | Traded 22-year old minor league starting pitcher R. Nye to the Boston Red Sox, getting nothing in return. |
| Thursday, October 6th, 1966 | | Signed LF C. Hinton to a 2-year contract extension worth a total of $329,200. | | Signed MR E. Hobaugh to a 3-year contract extension worth a total of $728,400. |
| Friday, September 16th, 1966 | | Purchased the contract of 1B T. Brown from Triple A Spokane. |
| Thursday, December 2nd, 1965 | | Signed free agent CF J. Landis to a 1-year contract worth a total of $57,200. |
| Tuesday, November 16th, 1965 | | MR D. Aust received a 1-year contract through automatic renewal worth a total of $24,774. | | CF D. Snider becomes a free-agent. | | C M. Brumley received a 1-year contract through automatic renewal worth a total of $24,774. | | MR D. Coombs received a 1-year contract through automatic renewal worth a total of $24,774. | | 1B T. Francona becomes a free-agent. | | MR P. Mikkelsen received a 1-year contract through automatic renewal worth a total of $24,774. | | SS D. Groat becomes a free-agent. | | 1B B. Zipfel received a 1-year contract through automatic renewal worth a total of $24,774. | | CF R. Repoz received a 1-year contract through automatic renewal worth a total of $24,774. | | RF J. Northrup received a 1-year contract through automatic renewal worth a total of $24,774. | | SS J. Kennedy received a 1-year contract through automatic renewal worth a total of $24,774. | | Purchased the contract of RF K. Berry from Triple A Spokane. | | Purchased the contract of LF D. Lock from Triple A Spokane. | | Traded 36-year old starting pitcher D. Mossi to the Cincinnati Reds, getting 29-year old starting pitcher J. Tsitouris in return. |
| Saturday, November 13th, 1965 | | SP B. Baird received a 1-year contract through arbitration worth a total of $215,204. | | MR S. Dillon received a 1-year contract through arbitration worth a total of $43,332. | | MR J. Hannan received a 1-year contract through arbitration worth a total of $158,976. | | CL S. Hamilton received a 1-year contract through arbitration worth a total of $80,755. | | 3B D. Allen received a 1-year contract through arbitration worth a total of $458,656. | | LF C. Hinton received a 1-year contract through arbitration worth a total of $81,519. | | MR E. Hobaugh received a 1-year contract through arbitration worth a total of $156,000. | | SP D. Stenhouse received a 1-year contract through arbitration worth a total of $56,746. | | LF D. Lock received a 1-year contract through arbitration worth a total of $55,872. | | C K. Retzer received a 1-year contract through arbitration worth a total of $37,448. |
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